What is the characteristic presentation of Grade III Acne?

Grade III Acne is characterized by a more severe presentation compared to the earlier grades of acne. Individuals with this type of acne typically experience significant inflammation, which manifests as redness and swelling. The presence of many comedones, which are clogged pores that appear as either closed (whiteheads) or open (blackheads), is a hallmark of this grade. Additionally, Grade III Acne includes papules and pustules, which are the small, raised, inflamed lesions filled with pus. This combination of symptoms indicates a more severe inflammatory response and a higher population of bacteria within the follicles, reflecting a significant progression in acne severity that distinguishes it from milder forms of the condition.

The other options reflect less severe types of acne presentations. For instance, comedones only represent a much earlier and milder stage, while few closed comedones and mild inflammation would indicate a lower grade of acne. Furthermore, having only papules without pustules shows a less invasive condition than what is seen in Grade III. Thus, the comprehensive inflammatory response and variety of lesions in Grade III (including both papules and pustules in conjunction with numerous comedones) underscores why this specific answer is considered correct.